There is a difference, but it has nothing to do with Feng Shui, but with the flow of people.
Usually, people only want to go to the first floor because it is convenient and can go up to the first floor.
Basically, they will not go to the second floor to buy things.
I have seen two supermarkets, one on the first floor and one on the second floor. The one on the second floor can also park cars, which should be said to be very convenient, but people just don't
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Went there, but the supermarket on the second floor closed down soon after.