It is a phenomenon in which lipid components accumulate abnormally in non-fat cells due to metabolic abnormalities. It is characterized by the appearance of fat droplets in the cytoplasm that are normally invisible under a light microscope, or intracytoplasmic fat droplets. increase. The main component of lipid droplets is neutral fat (triglyceride), which may also contain phospholipids and cholesterol esters. In paraffin sections, lipid droplets are dissolved by lipid solvents such as alcohol and xylene, so they appear vacuole-like, and sometimes Not easily distinguished from vesicular degeneration. Frozen sections and fat staining with Sudan III, Sudan Black B or osmotic acid are required to display; the lipid droplets appear orange-red when stained with Sudan III, and black when stained with Sudan black or osmic acid. It mainly occurs in the heart, liver, kidney, etc. I don’t know much about this problem, so I can only help to check the information, which may not be of great help!
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That’s very good, thank you.