The main entrance of my living room faces east, and the painting of running water to make money is hung on the west wall opposite. Does it have any effect on Feng Shui?

Running water painting is very suitable for hanging in the living room, and it won't have any feng shui influence. It means wealth is like running water. But in many landscape paintings, water flows inward, because water makes money, and only when water flows inward can it make money. If you believe in geomantic omen, you'd better find a geomantic omen master to come to your house and figure out where your geomantic omen is now and which side is suitable for painting.