Yes
As long as you are not afraid of getting dirty.
Of course, the squirrel hopes that the place where it lives is as big as possible, the bigger it can run, the more comfortable it can be and the more it can do as it pleases.
However, no matter where it is kept, it must be a closed-loop environment. Otherwise, it will run away, and once it runs away, it will never come back.
And they especially like to crawl into corners and dark places. Once you get out, you can't come back.
Furthermore, squirrels urinate wherever they go. They are too dirty. It is better to buy a larger cage and keep them in cages!