How to judge novel coronavirus?

differential diagnosis

(1) The mild manifestations of novel coronavirus infection should be differentiated from upper respiratory tract infections caused by other viruses.

(2) novel coronavirus is mainly differentiated from influenza virus, adenovirus, respiratory syncytial virus and other known viral pneumonia and mycoplasma pneumoniae infections. Especially for suspected cases, rapid antigen detection and multiplex PCR nucleic acid detection should be adopted as far as possible to detect common respiratory pathogens.

(3) It should also be differentiated from non-infectious diseases, such as vasculitis, dermatomyositis and organized pneumonia.

Seven. Case discovery and report

Medical staff of various medical institutions at all levels should immediately carry out single-room isolation treatment, in-hospital expert consultation or attending physician consultation after discovering suspected cases that meet the definition of cases. If they are still considered as suspected cases, they should report directly to the network within 2 hours, collect samples for novel coronavirus nucleic acid detection, and immediately transfer the suspected cases to designated hospitals on the premise of ensuring the safety of transshipment. Even if common respiratory pathogens are positive, patients who have close contact with novel coronavirus-infected people should be tested for novel coronavirus in time.

Eight, treatment

(a) according to the condition to determine the treatment site.

1. Suspected and confirmed cases should be treated in isolation in designated hospitals with effective isolation and protection conditions. Suspected cases should be treated in isolation in a single room, and confirmed cases can be treated in the same ward.

2. Critical cases should be sent to ICU for treatment as soon as possible.

(2) general treatment.

1. Stay in bed, strengthen supportive treatment, and ensure sufficient calories; Pay attention to the balance of water and electrolyte and maintain the stability of internal environment; Closely monitor vital signs, finger oxygen saturation, etc.

2. Monitor blood routine, urine routine, CRP, biochemical indexes (liver enzyme, myocardial enzyme, renal function, etc. ), coagulation function, arterial blood gas analysis, chest imaging, etc. According to the condition. Cytokine detection is feasible if conditions permit.

3. Give effective oxygen therapy measures in time, including nasal catheter, mask oxygen supply and nasal large flow oxygen therapy.

4. Antiviral treatment: You can try interferon-α (adult, 5 million U each time or the same dosage, 2mL sterile water for injection, twice a day), lopinavir/ritonavir (adult, 200mg/50mg/ capsule, 2 capsules each time, twice a day, and the course of treatment is no more than 10 day), and ribavirin (0. Intravenous drip 2-3 times a day, the course of treatment shall not exceed 10 day), chlorine phosphate (500mg for adults, twice a day, the course of treatment shall not exceed 10 day), and abidol (200mg for adults, the course of treatment shall not exceed 10 day). Attention should be paid to the adverse reactions such as diarrhea, nausea, vomiting and liver function damage related to lopinavir/ritonavir, as well as the interaction with other drugs. To further evaluate the efficacy of experimental drugs currently used in clinic. It is not recommended to use three or more antiviral drugs at the same time, and relevant drugs should be stopped when intolerable toxic and side effects occur.

5. Antibiotic treatment: Avoid blind or improper use of antibiotics, especially the combined use of broad-spectrum antibiotics.