The younger brother of the first generation: Senju Tobirama.
Granddaughter of the first generation: Master of Thousand Hands
Grandson of the first generation: Nawaki (Gang Shou's younger brother)
Three generations of disciples (Sarutobi Hiruzen): Jiraiya, orochimaru, Master of Thousand Hands.
Son of three generations: Sarutobi Asuma
Grandson of three generations: Sarutobi Konohamaru (nephew of Asma)
The fourth generation () disciples:, Lin,.
Fourth generation wife: Uzumaki Kushina.
Son of IV: Naruto Usagi.
Disciples of Five Dynasties (Master of Thousand Hands): Silent, Haruno Sakura and Yamanaka Ino.
Five generations of lovers: Kato Dan (killed)
Jiraiya's apprentices: Namikaze Minato, Naruto, Yahiko, Nagato and Xiaonan.
Orochimaru's disciples: Mitarashi Anko and Sasuke Uchiha.
Hatake Kakashi's subordinates: Naruto Usagi, Sasuke Uchiha (defected), Haruno Sakura, Sai (instead of Sasuke)
Should meet the requirements!