Gout is a common and complicated type of arthritis, which can occur at all ages, and the incidence rate of male is higher than that of female. Gout patients often have sudden joint pain at night, with acute onset and severe pain, edema, redness and inflammation at the joints, and the pain gradually decreases until it disappears, lasting for several days or weeks. When the pain breaks out, patients will wake up in the middle of the night. Some patients describe the pain as similar to burning their big toes. The most common joint is the big toe (medical term: the first metatarsal), but the joint is not limited to this, and it is also common in joints such as hands, knees and elbows.
The diseased joints will eventually become inflamed and inflamed. After edema, the tissue will become soft and the activity will be limited, which will eventually affect daily life. These symptoms will recur, so once there is a strong and sudden pain in the joints, you should see a doctor in time to manage and prevent the symptoms. If not treated in time, the consequence of delay is that the pain will become more and more severe and unbearable. If you have a fever at this time, it means that there is already inflammation. Moreover, the joint itself will be damaged, leading to kidney calculi's disease, even renal failure, which is life-threatening.
The rapid analgesia of gout requires the timely application of analgesic drugs: there are three commonly used drugs. The first drug is colchicine, which can reduce the activity and phagocytosis of white blood cells, reduce the formation of lactic acid, reduce the deposition of uric acid crystals, reduce the inflammatory reaction and play an analgesic role. The second kind of non-steroidal anti-inflammatory drugs mainly use diclofenac sodium or ibuprofen to achieve anti-inflammatory and analgesic effects by inhibiting the synthesis of prostaglandin. The third kind is glucocorticoid, mainly prednisone, etc. , can reduce the release of inflammatory cells, reduce inflammatory reaction, and control pain by suppressing immunity. Don't bear the burden during acute pain, pay attention to rest.