Why does gout attack so much at night? How to prevent arthritis?

1. Why does gout like to attack at night?

1. Dehydration

As the night goes on, people feel they lose water through breathing, perspiration, getting up at night, etc., but they are unable to drink water anytime and anywhere like during the day. Replenishing water can easily cause the body to become dehydrated, causing blood extraction, increased blood uric acid concentration, and crystal deposition, causing gout attacks.

2. Low hormones

Hormonal drugs have the effect of inhibiting inflammation, which can effectively prevent gout attacks and at the same time reduce the pain symptoms during the attack. However, the metabolism of hormone drugs has an obvious circadian rhythm: it is lowest at 0 to 2 am in the morning, gradually increases from 3 to 5 am, reaches a peak at 6 to 8 am, and then gradually decreases. It happens that the metabolism of hormone drugs is reduced in the middle of the night, which gives the opportunity for gout attacks.

3. Temperature decrease

The solubility of urate is related to temperature. According to relevant experimental measurements, the solubility of urate in saline water at 37°C is 416 μmol/L, which is very close to the confirmed value of hyperuricuria of 420 μmol/L. The normal core body temperature of the human body is 37°C, and at the toes that are far away from the center and have ultra-thin skin, 25°C is exactly the same temperature as the toes in the morning. At this time, the solubility of uric acid is reduced by about half, and it is easiest to precipitate. It crystallizes, so the toes are most susceptible to the disease.

4. Insufficient oxygen

Many people with ventilation problems will "snore" at night, especially those with obesity. The snoring starts and stops, followed by constant snoring. Sleep apnea, when severe, can lead to a decrease in the body's blood oxygen concentration. In order to better solve the lack of oxygen in the body, the body's nucleoside metabolism is increased. The final result is that although the patient skips meals and falls asleep, a lot of endogenous "purines" are produced in the body, and the end product of purine metabolism happens to be uric acid, which causes gout attacks. 2. How to prevent arthritis?

1. Control weight

Obesity is a problem that should be paid attention to regardless of age. Obesity can cause arthritis, which is understandable, so it should be controlled with a reasonable diet and more exercise. It is very important to reduce the weight and relieve the pressure on the body. We should also pay attention to exercise. We should choose exercises that are less harmful to joints, such as walking, Tai Chi, swimming, etc., carry out outdoor activities frequently, exercise under the sun and sweat more, which can help eliminate toxins from the body. Toxins can effectively prevent the occurrence of arthritis.

2. Efficient daily life

The environment in which we live must maintain ventilation, sunlight, dryness in the room, and fresh air. The quilts should be dried frequently to avoid germs. of growth. Use warm water to wash your face and brush your teeth in the morning and morning, and squeeze your feet with boiled water at night. This is particularly beneficial for joint repair. It can promote blood circulation in the legs and effectively prevent the occurrence of rheumatoid arthritis.

3. Eat a reasonable diet

Osteoarthritis patients must maintain a reasonable diet, absorb sufficient nutrients to provide joints with balanced nutrition, and also effectively prevent arthritis. produce.

4. Moderate exercise

Swimming is a full-body exercise that is more suitable for middle-aged and elderly people. This fitness exercise basically puts no pressure on the joints of the whole body, but it can improve heart function, make you strong and strong, reduce abdominal fat, maintain a uniform body shape, and achieve the purpose of strengthening your physique without harming the joints. It is especially suitable for Many patients with osteoarthritis. This exercise can be carried out every day, and each swim does not need to be too long or overexert the body.