I don't think Watergate and Uchiha Itachi can be compared, but from the perspective of endurance, we should make a comprehensive comparison from the following aspects.
First, sacrifice your life for justice.
Both of them sacrificed themselves for Muye Village, and Watergate sacrificed to control and seal Kyubi no Youko who escaped.
Uchiha Itachi killed the whole family for the future of Muye Village, always acting in secret with a stigma, collecting intelligence, and finally sacrificing for his younger brother.
Watergate is like a policeman who died in the war, and Uchiha Itachi is a humiliating undercover.
Both of them are great. If we have to divide them into 1.2, Uchiha Itachi, who endured humiliation, is slightly better this round.
Second, forward-looking
Chakra, half of Kyubi no Youko, sealed himself, the other half of chakra wind, guided Naruto, leaving many small organs for Naruto and his father to meet in the back.
Uchiha Itachi killed the whole family, left his favorite brother, met Sasuke by chance again and again, and helped Sasuke to open up sharingan and all kinds of extreme endurance again and again.
Both of them have made a lot of predictions and preparations for the future of their most important people. This round is neck and neck.
Third, achievements.
Watergate is the fourth generation of Huo Ying, and Uchiha Itachi is a genius boy who joined the dark side at the age of 13.
Looking at the superficial achievements, Watergate left a lot of weasels, but the weasels carried a lot behind them, so it is difficult to judge who is tall and who is low.
Fourth, Ninjutsu
Watergate, also known as golden lightning, has super instantaneous movement ability. In addition, there are seals of corpses and ghosts, bijuu pattern and immortal pattern.
Skunks have the skills of Harle, Nenghu, Zhao Tian, Isobo and Fireball.
Both of them have their own housekeeping skills, but they are not in the same era, so it is difficult to say a level, but from the author's description of Watergate, Watergate should be better in endurance.