How to eliminate teams in 100-city league

If there are many teams and a wide geographical area, they can be grouped by region first. For example, it can be divided into 8 regions, and each region will be promoted to 4 teams to form 32 teams to enter the semi-finals. Because cities are different, the regional and semi-finals adopt the competition system of drawing lots by non-nuclear teams, single game and elimination one by one. Both the rematch and the rematch can use tie overtime until the penalty is decided. The key is the balance between the business divisions and the promotion teams of each business division. In the semi-finals, in addition to the consideration of strength, teams of 16, 32, 64 must be formed in the end, so that there will be no team bye. From the perspective of playing more games, we can consider implementing the home and away system. In addition, whether to set up a seed team can also be considered in the competition area. My opinion is not to set up a seed team, because the number of amateur teams is not fixed and variable, and it is not impossible for the seed team to be at the bottom.