The first batch of domestic human papillomavirus vaccine is bivalent human papillomavirus vaccine, and the Second People's Hospital of Xiangzhou District is currently planning to inoculate the first batch of domestic human papillomavirus vaccine, which is expected to be listed in mid-July. If necessary, the public can consult the vaccination clinic of the hospital to see if it is in stock.
At present, the price of domestic bivalent HPV vaccine is 329 yuan/needle, which is nearly half cheaper than imported similar vaccines. (PS: imported bivalent vaccine 580 yuan/injection).
Do I need to make an appointment for domestic cervical cancer vaccine? At present, the nine-valent HPV vaccine in Zhuhai is still in short supply, and the method of making an appointment to shake the number is temporarily adopted;
Bivalent HPV vaccine and tetravalent HPV vaccine do not need to participate in the lottery. Citizens and friends can go directly to the vaccination clinic for vaccination. Before vaccination, it is recommended to consult the clinic in advance whether there is a vaccine available for vaccination.
Where to inoculate HPV vaccine in Zhuhai At present, there is sufficient supply of bivalent HPV vaccine in Zhuhai, tetravalent HPV vaccine can basically meet the demand at present, and there is a serious shortage of nine-valent HPV vaccine.
Because the nine-valent HPV vaccine is still in short supply, the method of making an appointment to draw lots for vaccination is currently adopted; Bivalent HPV vaccine and tetravalent HPV vaccine do not need to participate in the lottery. Citizens and friends can go directly to the vaccination clinic for vaccination. Before vaccination, it is recommended to consult the clinic in advance whether there is a vaccine available for vaccination.
Frequently asked questions about HPV vaccine 1, what is the difference between bivalent, tetravalent and nonavalent human papillomavirus vaccines?
The bivalent HPV vaccine contains human papillomavirus HPV 16 and18; The tetravalent HPV vaccine includes type 6, 1 1, 16 and 18; The nine-valent HPV vaccine includes types 6, 1 1, 16, 18, 3 1, 33, 45, 52 and 58. However, all three vaccines can target the above-mentioned high-risk human papillomavirus, prevent human papillomavirus-related diseases, and fight against HPV 16 and 18 infections, with remarkable effects. Compared with bivalent HPV vaccine, tetravalent HPV vaccine can also prevent genital warts caused by HPV6 and 1 1, and nonavalent HPV vaccine will increase the proportion of preventing cervical cancer from 70% to 90%.
At present, the World Health Organization's position paper on HPV vaccine has no preference for the recommendation of three vaccines. Citizens can voluntarily vaccinate at their own expense according to the types and prices of vaccines and their age conditions.
2. What are the requirements for the vaccination age of bivalent, tetravalent and nonavalent human papillomavirus vaccines?
At present, the age of vaccination approved in Chinese mainland is:
Bivalent HPV vaccine: suitable for women aged 9-45. The inoculation process is as follows: 0 1 and June, with 1 dose and ***3 doses respectively; There are also vaccine varieties. 9- 14-year-old females were inoculated with 1 dose and ***2 doses at the 0 th and 6 th months respectively according to the vaccination process.
Tetravalent HPV vaccine: suitable for women aged 20-45. According to the inoculation process, inoculate 1 dose at the 0 th, 2 nd and 6 th month, inoculate 1 dose each time, with 3 doses of * * *.
9-valent HPV vaccine: suitable for 16 ~ 26-year-old women. The inoculation process is: 1 dose, with ***3 doses at the 0, 2 and 6 months respectively.
3. After being vaccinated with bivalent and tetravalent human papillomavirus vaccines, can I still be vaccinated with nine-valent HPV vaccine?
At present, there is no clinical data to support the exchange of nine-valent HPV vaccine with other HPV vaccines. The World Health Organization's position paper on HPV vaccine has no preference for the three vaccine recommendations. From the point of view of public health, bivalent, tetravalent and nonavalent vaccines can provide considerable immunogenicity and protective efficacy in preventing cervical cancer (mainly caused by HPV 16 and HPV 18). According to the existing conditions, it is possible to vaccinate any of the three kinds of human papillomavirus vaccines.
According to the instructions of the nine-valent HPV vaccine, if someone wants to vaccinate the nine-valent HPV vaccine after three doses of the four-valent HPV vaccine, it will take at least 12 months to vaccinate, and the vaccination dose is three doses.
4. Can I get bivalent or tetravalent HPV vaccine after one or two injections instead of nine-valent HPV vaccine?
In 20 16, the American Advisory Committee on Immunization Strategy Implementation (ACIP) suggested that if the vaccination program started with tetravalent or bivalent HPV vaccine, the remaining dose could be replaced with nine-valent HPV vaccine to complete the whole vaccination program. However, according to the World Health Organization's position paper on HPV vaccine 20 17, there is very limited information about the safety, immunogenicity or effectiveness of the interchangeable use of three human papillomavirus vaccines. These vaccines have different characteristics, components and indications; In addition, the instructions for the use of tetravalent and nonavalent human papillomavirus vaccines specifically point out that there is no clinical data to support the interchangeable use of nonavalent human papillomavirus vaccines with other human papillomavirus vaccines. Therefore, even if there are a variety of HPV vaccines, efforts should be made to unify the vaccination procedures and use the same vaccine for each dose.
5. If you are vaccinated with HPV vaccine, you won't get diseases caused by human papillomavirus?
As we all know, no vaccine can protect 100%.
All HPV vaccines can provide a high level of protection (about 70%) against HPV 16 and 18. HPV vaccine also provides some cross protection for some types not included in the vaccine.
Nine-valent HPV vaccine increased the proportion of preventing cervical cancer from 70% to 90%, but failed to cover all high-risk human papillomavirus types; In addition, vaccination may also lead to immune failure. Therefore, the nine-valent HPV vaccine can not 100% prevent all infections or diseases caused by human papillomavirus, and cervical cancer screening is still needed as usual after vaccination.
6. How long can the protective efficacy of 6.HPV vaccine last? Is it enough to get three shots of vaccine for a program? Do you want to make up the call in the future?
Three doses of tetravalent HPV vaccine have been inoculated for more than 10 years, during which no breakthrough cases of cervical or genital diseases related to HPV6, 1 1, 16 and 18 occurred. Three doses of bivalent HPV vaccine were inoculated to prevent HPV 16 and HPV 18 infection and cervical lesions for 9 years. The efficacy of three doses of bivalent HPV vaccine in preventing infection and cervical/vulvar/vaginal lesions lasted for 6 years.
In the World Health Organization's position paper on HPV vaccine, there is no suggestion to strengthen immunization after re-vaccination.
7. Can women who have had sex be vaccinated against human papillomavirus?
Human papillomavirus infection is not a contraindication for vaccines. The risk of exposure to human papillomavirus increases with age, especially after sexual life begins. Therefore, the benefits of vaccination of young people with human papillomavirus will be higher.
Women who have had sexual life are not necessarily infected with human papillomavirus, and they can be vaccinated with human papillomavirus as long as they are at the age; Women who have had sexual life, even if infected with human papillomavirus, can prevent persistent human papillomavirus infection, prevent related diseases, and can also be vaccinated with HPV.
8. Can pregnant women and lactating women be vaccinated? What should I do if I get pregnant after vaccination?
Vaccination with HPV vaccine should not affect fertility. No direct or indirect adverse effects of human papillomavirus vaccine on reproduction, pregnancy and embryo development were found in animal experiments. Because there is no good controlled study, as a preventive measure, pregnant women are not recommended to be vaccinated with HPV. Vaccination against human papillomavirus should be avoided during pregnancy.
In clinical trials, it has not been observed that antibodies induced by HPV vaccine are secreted through breast milk, but many drugs can be secreted through breast milk, so lactating women should use them with caution.
If a woman is pregnant or ready to get pregnant, it is recommended to postpone or interrupt the vaccination and wait until the pregnancy is over.
9. Are there any side effects after vaccination of human papillomavirus?
There are few side effects and mild symptoms, such as rash, swelling and pain at the injection site. More serious side effects include: fever, nausea, dizziness, muscle weakness and paralysis; But like other vaccines, the advantages outweigh the disadvantages.
10, should I be tested for human papillomavirus before vaccination with nine-valent HPV vaccine?
No need. Human infection with human papillomavirus is a dynamic process, and it is not necessary to detect human papillomavirus before vaccination.
1 1, why can't I get a nine-valent HPV vaccine over the age of 26?
There is no clinical data on the effectiveness of the nine-valent HPV vaccine for people over 26 years old because the population selected in the clinical trial before the nine-valent HPV vaccine was approved for marketing in China was 16 ~ 26 years old. Therefore, at present, women over the age of 26 in China cannot be vaccinated with nine-valent HPV vaccine.